Botulinum toxin

The application of botulinum toxin is a highly effective and low-risk skin rejuvenation procedure. Although aesthetic medicine has been using it daily for several decades, it still ranks among the most frequently requested and performed treatments—and rightfully so. It effectively smooths dynamic wrinkles and also helps prevent their formation.

Botulinum toxin application has become synonymous with a more youthful-looking complexion. It can soften or even completely reduce visible wrinkles and effectively prevent new ones from forming. When used thoughtfully, it can accompany you on your journey toward graceful, natural aging for many years, delivering remarkable results.

Botulinum toxin: a proven method for wrinkle correction

Botulinum toxin can support the care of your appearance at any stage of life. Owing to its precise, unit-based application, it offers a highly versatile spectrum of effects tailored to individual needs. Younger clients frequently choose it as a preventive measure to relax facial muscles and inhibit the formation of expression lines—a practice often referred to as “baby botox.” In contrast, more mature clients may benefit from higher-intensity treatments designed to soften and correct established wrinkles, resulting in a naturally refreshed and rejuvenated appearance.

Which lines can be treated with botulinum toxin

Botulinum toxin is most commonly used to address wrinkles in the upper half of the face. Specifically, it is effective for treating:

  • Horizontal forehead lines
  • Frown lines between the eyebrows, also known as glabellar lines
  • Wrinkles in the outer eye corners, often called crow’s feet
  • Brow lift
  • Vertical lip wrinkles, also called lip lines or smokers’ lines


It is also suitable for non-invasive facial contouring, such as:

  • Gummy smile – by relaxing the muscle above the upper lip, a more balanced smile with less visible gum can be achieved
  • Masseter – injections into the chewing muscle can create a slimmer appearance of the cheeks and narrow the lower face
  • Platysma or the “Nefertiti lift” – a highly specific rejuvenation treatment for clients who overuse the muscles along the sides of the neck; by relaxing these muscles, the tension is reduced and the skin appears smoother

In addition to the treatments listed above, at Esthé we also use botulinum toxin to address excessive sweating.

I’d like to try botulinum toxin

What is botulinum toxin and how does it work?

Botulinum toxin is a neurotoxin produced by the bacterium Clostridium botulinum. It acts as a muscle relaxant by preventing the transmission of neurological signals from the brain to the targeted muscle. Botulinum toxin type A has been used for over 40 years as a significant therapeutic agent in neurology, ophthalmology and dentistry. Since the 1990s, it has become a cornerstone of aesthetic medicine.

What does the effect of botulinum toxin look like in aesthetic practice? If you frown frequently, the facial muscle responsible for drawing the eyebrows together becomes chronically overactive. This occurs at the expense of other facial muscles, leading to muscular imbalance, similar to what is observed in conventional physiotherapy. Repeated activation of this muscle also creates a pronounced line that gradually deepens over time. Through precise application of botulinum toxin, we are able to temporarily deactivate, release and relax this muscle. As a result, the wrinkle naturally smooths out.

How long does the effect of botulinum toxin last?

You will begin to notice the effects gradually within 2–7 days, with the full result developing after approximately 2 weeks. The effect typically lasts for 3–6 months and then naturally subsides without any permanent consequences.
With repeated treatments, this duration tends to extend slightly over time. You might expect that the procedure would need to be performed more frequently, but in fact, the opposite is true. By relaxing the targeted muscles, wrinkle formation slows down, and you gradually “unlearn” habitual expressions such as frowning or furrowing the forehead.

What does the treatment look like?

Botulinum toxin is injected using an extremely fine needle. In the selected area, the doctor will make a few tiny injections that you will hardly feel. For most clients, the procedure is completely painless. To ensure maximum comfort, we also offer the option of applying an anaesthetic cream beforehand.
The treatment is gentle and requires no special preparation. After approximately 15 minutes, including aftercare instructions, you can resume your usual daily activities.

Botulinum toxin must not be administered to: pregnant or breastfeeding women, individuals with disorders of neuromuscular transmission (e.g., myasthenia gravis), anyone with known hypersensitivity to any of the components of the preparation, individuals with any ongoing infectious illness (this includes anything from a mild cold to an active cold sore or mouth ulcer). On the day of treatment, it is essential to refrain from taking blood-thinning medications (e.g., warfarin, aspirin). Individuals with a history of botulism are resistant to botulinum toxin, meaning the treatment will not be effective for them.  

“Botox” – Myths, Concerns, and Media PerceptionBotox

The tabloids often fuel public fear that botulinum toxin will leave your face frozen into an expressionless mask, unable to convey even the slightest emotion. Media outlets eagerly showcase celebrities whose unnatural appearances are frequently the result of plastic surgery or poorly executed dermal fillers. This concern is not entirely unfounded. But why?

Due to its widespread popularity, botulinum toxin has fallen into unqualified hands—ranging from complete amateurs in beauty salons to inadequately trained doctors. Although aesthetic medicine works with minimal and completely safe doses compared to general medicine, botulinum toxin remains one of the most potent natural toxins and should always be treated with respect.

Botulinum toxin injections should always be administered by a doctor—one who is specifically trained in this field. A true expert has an in-depth understanding of facial anatomy and its intricacies, can tailor the treatment to individual needs, accurately estimate the precise dosage, and deliver it with millimetre precision to the correct depth and location on your face. By placing your trust in a skilled specialist, any concerns can be confidently put to rest. Our team consists exclusively of seasoned specialists who prioritise your health and natural appearance above all else.

I’d like to smooth my wrinkles with botulinum toxin

SEE BEFORE AND AFTER PHOTOS

 

FAQ – Frequently Asked Questions About Botulinum Toxin

 
 
 

Yes—and for overall facial rejuvenation, it is often highly advisable. As described above, botulinum toxin is typically used for the upper part of the face and specific dynamic wrinkles. For lines in the lower face or deeper creases, we may recommend complementary procedures such as mesotherapy or hyaluronic acid-based dermal fillers. Our doctors will always help you find the most suitable approach.

As for the synergy of laser treatments and botulinum toxin, it is also possible on the same day, you just need to choose the right order. For example, we will first perform laser rejuvenation and then inject botulinum toxin, but never the other way around. After applying botulinum toxin, you will have to postpone laser treatments for about 14 days until the botulinum toxin is properly absorbed.

 
 
 

Price list

Botulinum toxin Price
Initial examination (paid only on the 1st visit) 500 CZK
Wrinkles between eyebrows 2,300 - 3,900 CZK
Wrinkles on the forehead 2,300 - 3,100 CZK
Wrinkles around the eyes (outer eye corners) 3,100 - 5,400 CZK
Masseter (slimming of the jaw line) 6,000 - 9,000 CZK
Platysmal bands (neck wrinkles) 4,200 - 7,500 CZK
Hyperhidrosis treatment 9,000 - 13,000 CZK
Price for the application is determined by the number of units